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KMID : 0381219760080010051
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Journal of RIMSK
1976 Volume.8 No. 1 p.51 ~ p.60
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A case of xeroderma pigmentosum
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Abstract
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One case of classical Xeroderma pigmentosum with freckle, hypopigmentations and multiple basal cell epitheliomas on the face was confirmed by histopathological findings and characteristic clinical manifestations.
This disease is a genodermato3is characterized by extreme sun sensitivity, photophobia, freck-les, atrophy, telangiectases, kerato3e3, and finally malignant degeneration of the skin. It is rare and probably inherited autosomal racecsive trait. Recently, pathogenesis has been found that the sunlight damaged DNA strands cannot be repaired because of a deficiency of endonulease(Repairase).
This deficiency is probably of hereditary nature.
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